Clinical Trials Directory

Trials / Completed

CompletedNCT00633269

Study Assessing Metabolism, Excretion and Pharmacokinetics of a Poly (ADP-Ribose) Polymerase (PARP) Inhibitor in Patients With Solid Metastatic Tumours

Open, Non-Randomized, Single Centre Phase I Study to Assess the Metabolism, Excretion and Pharmacokinetics of a Single Oral 100 mg Dose of [14C]-AZD2281 (KU-0059436) in Patients With Advanced or Metastatic Solid Tumours Refractory to Standard Treatments

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
6 (estimated)
Sponsor
AstraZeneca · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Open, non-randomized, radiolabelled, single centre study designed to characterize the metabolism, excretion and pharmacokinetics of a single oral dose of 100 mg \[14C\]-radiolabelled AZD2281 (KU-0059436) in patients with advanced or metastatic solid tumours.

Conditions

Interventions

TypeNameDescription
DRUGAZD2281100mg Oral Dose

Timeline

Start date
2008-04-01
Primary completion
2008-10-01
Completion
2008-10-01
First posted
2008-03-12
Last updated
2009-01-14

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT00633269. Inclusion in this directory is not an endorsement.