Trials / Completed
CompletedNCT00632892
The Correlation Between Oxidative Stress and Indinated Contrast-Media Nephrotoxicity
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 80 (planned)
- Sponsor
- Far Eastern Memorial Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Clinically, iodinated contrast-medium (CM) is widely used in angiography and computerized tomography. CM-induced nephropathy (CMIN) is one major complication after application of CM. Therefore, how to prevent CMIN is always one of the hot topics concerned by nephrologists, cardiologists, and radiologists. The present study is aimed to determine the norepinephrine concentration, oxidative markers, and tubular damage markers in the urine samples of patients undergoing intravenous pyelography (IVP). The working hypothesis is high-osmolarity contrast media (HOCM) causes more oxidative stress and greater tubular damage than iso-osmolarity contrast media (IOCM).
Conditions
Timeline
- Start date
- 2007-12-01
- Primary completion
- 2008-01-01
- First posted
- 2008-03-11
- Last updated
- 2008-03-11
Locations
1 site across 1 country: Taiwan
Source: ClinicalTrials.gov record NCT00632892. Inclusion in this directory is not an endorsement.