Clinical Trials Directory

Trials / Completed

CompletedNCT00631917

A Study Evaluating the Gastrointestinal (GI) Safety and Tolerability of Aliskiren Compared to Ramipril in Essential Hypertension

A 54 Week, Randomized, Double-blind, Parallel-group, Multicenter Study Evaluating the Long-term Gastrointestinal (GI) Safety and Tolerability of Aliskiren (300 mg) Compared to Ramipril (10 mg) in Patients With Essential Hypertension

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
774 (actual)
Sponsor
Novartis · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

This study will evaluate the long-term gastrointestinal (GI) safety and efficacy of aliskiren (300 mg) compared to ramipril (10mg) in patients ≥ 50 years with essential hypertension.

Conditions

Interventions

TypeNameDescription
DRUGAliskirenAliskiren 300 mg once a day
DRUGRamiprilRamipril 10 mg once a day
OTHERPlacebo to RamiprilPlacebo capsules to match ramipril.
OTHERPlacebo to AliskirenPlacebo tablets to match aliskiren.

Timeline

Start date
2008-02-01
Primary completion
2009-09-01
Completion
2009-09-01
First posted
2008-03-10
Last updated
2011-07-12
Results posted
2011-06-21

Locations

7 sites across 7 countries: United States, Argentina, Colombia, France, Germany, India, Spain

Source: ClinicalTrials.gov record NCT00631917. Inclusion in this directory is not an endorsement.