NCT00630903

PUVA Versus PUVA + IFN Alpha 2a in Mycosis Fungoides

Prospective, Randomized Multicentic to Compare PUVA+IFN Alpha 2a vs PUVA Alone in Mycosis Fungoides Stages Ia, Ib or IIa.

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 54 (actual)
• Sponsor: Madrilenian Group of Cutaneous Lymphomas · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine if combination of PUVA with interferon alpha is better than PUVA alone to treat mycosis fungoides stage Ia Ib or IIa.

Conditions

• Cutaneous T-Cell Lymphoma (Mycosis Fungoides)

Interventions

Type	Name	Description
DRUG	PUVA (8MOP + UVA) + IFN	Weeks 3-24: 8.MOP: 0.6 MG/K, 3 times a week, 2 hours pre UVA irradiation (1-2 jul/cm2 according to phototype, increasing until 10 Jul/cm2, if tolerated) IFN: week1: 3, 6 and 9 MU (Mon, Wed, Fry). Weeks 2-24: 9MU 3 times a week)
DRUG	PUVA (8-MOP + UVA)	Weeks 1-24: 8.MOP: 0.6 MG/K, 3 times a week, 2 hours pre UVA irradiation (1-2 jul/cm2 according to phototype, increasing until 10 Jul/cm2, if tolerated)

Timeline

• Start date: 2000-01-01
• Primary completion: 2003-01-01
• First posted: 2008-03-07
• Last updated: 2008-03-07

Locations

9 sites across 1 country: Spain