NCT00629538

Therapeutic Thoracentesis for Patients With Congestive Heart Failure and Large Pleural Effusion

Effect of Therapeutic Thoracentesis on Cardiopulmonary Function in Patients With Congestive Heart Failure Complicated With Large to Massive Pleural Effusion

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Taipei Medical University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Transudative pleural effusions are a common manifestation of patients with congestive heart failure. Severe dyspnea and respiratory failure may develop in those with large effusions, which in general show poor response to medical treatment. Therapeutic thoracenteses (TT) may be indicated in these patients and can produce marked relief of symptoms. However, the underlying effect of TT on gas exchange and respiratory mechanics in theses patients remains unclear. The researchers' hypothesis is that,TT may improve arterial oxygenation and respiratory mechanics in patients with congestive heart failure complicated by large pleural effusions.

Conditions

• Congestive Heart Failure
• Transudative Pleural Effusion

Interventions

Type	Name	Description
PROCEDURE	Therapeutic thoracentesis	Thoracentesis was performed with drainage of 500 ml of pleural fluid first and every 200 ml thereafter until pleural pressure was lower than -20 cm H2O, chest discomfort developed, or no more pleural fluid could be removed.

Timeline

• Start date: 2007-03-01
• Primary completion: 2009-07-01
• Completion: 2009-07-01
• First posted: 2008-03-06
• Last updated: 2010-12-30

Locations

1 site across 1 country: Taiwan