Trials / Unknown
UnknownNCT00628056
Mechanisms Responsible for Cardiac and Skeletal Muscle Energetic Impairment in Diabetes
- Status
- Unknown
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 75 (estimated)
- Sponsor
- University Hospital Birmingham · Academic / Other
- Sex
- All
- Age
- 16 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Diabetes increases the risk of heart failure. This is mainly due to a disease of the blood vessels supplying the heart muscle and/or high blood pressure, but abnormal metabolism may also contribute. We plan to study the mechanisms involved in this abnormal metabolism, whilst also assessing the effects of a drug called Perhexiline which improves the abnormal metabolism that is present in diabetic patients before the development of heart failure.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Perhexiline | Intervention with Perhexiline/Placebo at 100mg twice a day for 2 weeks |
Timeline
- Start date
- 2006-10-01
- Primary completion
- 2009-04-01
- Completion
- 2009-04-01
- First posted
- 2008-03-04
- Last updated
- 2008-03-04
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT00628056. Inclusion in this directory is not an endorsement.