NCT00627406

Triggering of Final Oocyte Maturation With GnRHa (Buserelin) in GnRH Antagonist Cycles

A Prospective Randomised Study to Evaluate the Effect of Triggering Ovulation With GnRHa (Buserelin) and Low Dose hCG (Pregnyl) as Compared to the Use of Conventional Doses of hCG (Pregnyl)

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 384 (actual)
• Sponsor: Regionshospitalet Viborg, Skive · Academic / Other
• Sex: Female
• Age: 20 Years – 39 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to possibly further improve the clinical outcome and explore the incidence of OHSS in patients, who have final oocyte maturation with GnRHa (Buserelin) in GnRH antagonist IVF/ICSI cycles

Conditions

• OHSS (Ovarian Hyperstimulation)

Interventions

Type	Name	Description
DRUG	Buserelin and Pregnyl	Subcutaneous injection 0.5 mg and 1500 IU
DRUG	Pregnyl	Subcutaneous injection 5000 IU
DRUG	Buserelin and Pregnyl	Subcutaneous injection 0,5 mg and 1500 IU + 1500 IU after 7 days
DRUG	Pregnyl	Subcutaneous injection 5000 IU

Timeline

• Start date: 2009-01-01
• Primary completion: 2011-12-01
• Completion: 2011-12-01
• First posted: 2008-03-03
• Last updated: 2013-11-27
• Results posted: 2013-11-27

Locations

1 site across 1 country: Denmark