NCT00626912

PRET: Patients Prone to Recurrence After Endovascular Treatment

PRET: Patients Prone to Recurrence After Endovascular Treatment. A Randomized Trial Comparing Platinum and Hydrogel-coated Coils

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 447 (actual)
• Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The PRET study aims at comparing two types of coils used in the endovascular treatment of intracranial aneurysms. The first type made of platinum has been used for more than 15 years. The other, referred to as hydrocoil, containing in addition to platinum a polymer layer that expands when in contact with blood, has been in use since 2002. The hypothesis of the PRET study is that the newer hydrocoil will be more effective and yet as safe as the older platinum coil.

Conditions

• Intracranial Aneurysm
• Subarachnoid Hemorrhage

Interventions

Type	Name	Description
PROCEDURE	endovascular coil embolization	standard endovascular coil embolization with or without adjunct techniques

Timeline

• Start date: 2007-06-01
• Primary completion: 2015-10-01
• Completion: 2015-12-01
• First posted: 2008-02-29
• Last updated: 2019-03-26
• Results posted: 2019-03-01

Locations

32 sites across 6 countries: United States, Canada, Chile, France, Japan, United Kingdom