Trials / Completed
CompletedNCT00626080
Insulin Detemir Action in Cerebro
Effects of INsulin dEtemiR and Neutral protaminE Hagedorn (NPH) Insulin on BRain glucOse Metabolism: a Study in Persons With Type 1 Diabetes
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- Amsterdam UMC, location VUmc · Academic / Other
- Sex
- Male
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
The aim of this study is to test the hypothesis that subcutaneous administration of insulin detemir, as compared to insulin NPH, leads to a more pronounced effect on cerebral glucose metabolism and/or cerebral blood flow in brain regions associated with appetite regulation, to account for the reported difference in weight.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Insulin detemir | 100 IU/ml, QD, dose individually adjusted, to be used for a period of 12 weeks; in combination with insulin aspart TID |
| DRUG | Insulin NPH | 100 IU/ml, QD, dose individually adjusted, to be used for a period of 12 weeks; in combination with insulin aspart TID |
Timeline
- Start date
- 2009-01-01
- Primary completion
- 2011-12-01
- Completion
- 2011-12-01
- First posted
- 2008-02-29
- Last updated
- 2011-12-30
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT00626080. Inclusion in this directory is not an endorsement.