Clinical Trials Directory

Trials / Completed

CompletedNCT00624351

Study of Epratuzumab in Serologically-positive Systemic Lupus Erythematosus (SLE) Patients With Active Disease

A Phase IIb Randomized, Double-blind, Placebo-controlled, Dose and Dose Regimen-ranging Study of the Safety and Efficacy of Epratuzumab in Serologically-positive Systemic Lupus Erythematosus (SLE) Patients With Active Disease

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
227 (actual)
Sponsor
UCB Pharma · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary objective of the study is to assess the dose response and the dose frequency of epratuzumab in patients with SLE.

Conditions

Interventions

TypeNameDescription
BIOLOGICALEpratuzumabEpratuzumab at a concentration of 10 mg/mL prepared in 17.5 ml vials for slow intravenous infusion using only Phosphate buffered Saline (PBS) as a vehicle/buffer for the infusion procedure.
OTHERPlaceboPhosphate-buffered Saline (PBS) infusion.

Timeline

Start date
2008-01-01
Primary completion
2009-08-01
Completion
2009-08-01
First posted
2008-02-27
Last updated
2011-09-12

Locations

53 sites across 11 countries: United States, Belgium, Brazil, Hong Kong, Hungary, India, Lithuania, Poland, Spain, Ukraine, United Kingdom

Source: ClinicalTrials.gov record NCT00624351. Inclusion in this directory is not an endorsement.