NCT00623142

The Protective Effects Of Treatment With Hyperbaric Oxygen Prior To Bypass Heart Surgery

The Effects of Hyperbaric Oxygen Preconditioning On Cardiovascular Protection & Ischemic Reperfusion Injury

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 81 (actual)
• Sponsor: Hull University Teaching Hospitals NHS Trust · Other Government
• Sex: All
• Age: 20 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study was to determine if treating patients who have coronary heart disease with hyperbaric oxygen (HBO) prior to coronary artery bypass graft (CABG) surgery reduces injury to the heart and vascular system during and after surgery. Furthermore, this study also aims to identify some of the post CABG clinical effects of HBO treatment prior to CABG.

Conditions

• Myocardial Reperfusion Injury
• Cytoprotection

Interventions

Type	Name	Description
DRUG	Hyperbaric Oxygen	100% Oxygen at 2.4 ATA for 30 minutes followed by 5 minutes break followed by 100% Oxygen at 2.4 ATA for another 30 minutes. This intervention was given about 4 to 5 hours prior to CABG

Timeline

• Start date: 2005-01-01
• Primary completion: 2007-01-01
• Completion: 2008-01-01
• First posted: 2008-02-25
• Last updated: 2019-07-15

Locations

1 site across 1 country: United Kingdom