Clinical Trials Directory

Trials / Completed

CompletedNCT00623103

Long-term Safety of Rivastigmine Capsule and Patch in Patients With Mild to Moderately-severe Dementia Associated With Parkinson's Disease (PDD)

A 76-week Prospective, Open-label, Multicenter Study to Evaluate the Long-term Effect of Rivastigmine Capsule and Transdermal Patch on Worsening of the Underlying Motor Symptoms of PD in Patients With Mild to Moderately Severe Dementia Associated With Parkinson's Disease (PDD)

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
583 (actual)
Sponsor
Novartis · Industry
Sex
All
Age
50 Years – 85 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to provide long-term safety data for rivastigmine capsule and transdermal patch treatments, in particular the effect of rivastigmine on worsening of the underlying motor symptoms of Parkinson's Disease (PD), in patients with mild to moderately severe dementia associated with PD.

Conditions

Interventions

TypeNameDescription
DRUGRivastigmine capsuleRivastigmine capsules orally twice a day. Target dose 12 mg/day.
DRUGRivastigmine transdermal patchRivastigmine patch once a day in the morning, worn for 24 hours. Target dose 10 cm\^2/day delivering 9.5 mg over a 24 hour period.

Timeline

Start date
2008-01-01
Primary completion
2010-11-01
First posted
2008-02-25
Last updated
2011-11-28
Results posted
2011-11-28

Locations

127 sites across 13 countries: United States, Argentina, Australia, Austria, Belgium, Canada, France, Germany, Italy, Netherlands, Spain, Turkey (Türkiye), United Kingdom

Source: ClinicalTrials.gov record NCT00623103. Inclusion in this directory is not an endorsement.