NCT00622934

Relationship Between Erythropoietin Administration and Stress Responses in Trauma Patients

Relationship Between Clinical Recovery and Oxidative Stress and Inflammation Following Usage of Erythropoietin in Admitted Traumatic Patient In Intensive Care Unit

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Tehran University of Medical Sciences · Academic / Other
• Sex: All
• Age: 40 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether Erythropoietin decrease stress responses and inflammation in trauma patient.

Detailed description

Transfusion of blood products has many disadvantages. Erythropoietin is used to increase red blood cells production and decrease such disadvantages.In some studies anti inflammatory effects is shown for Erythropoietin. One of the most problems in the intensive care unit is stress response. we are going to evaluate effects of erythropoietin on oxidative stress and inflammation in trauma patient in intensive care unit.

Conditions

• Multiple Trauma

Interventions

Type	Name	Description
DRUG	erythropoietin	300mg/kg erythropoietin 3 times on the first week of admission
DRUG	placebo	placebo

Timeline

• Start date: 2007-07-01
• Primary completion: 2008-05-01
• Completion: 2008-05-01
• First posted: 2008-02-25
• Last updated: 2010-11-18

Locations

1 site across 1 country: Iran