NCT00615849

Efficacy of the Additional Mechanical Pleurodesis for Surgical Management of Primary Spontaneous Pneumothorax

Phase III Study of Evaluation of the Efficacy of Additional Mechanical Pleurodesis After Thoracoscopic Wedge Resection for the Management of Primary Spontaneous Pneumothorax

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 1,440 (actual)
• Sponsor: Seoul National University Bundang Hospital · Academic / Other
• Sex: All
• Age: 16 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

For the definite treatment of primary spontaneous pneumothorax(PSP), thoracoscopic bleb obliteration with pleural adhesive procedure is generally accepted as a standard. But additional pleurodesis is potentially useless procedure on the parietal pleura for treating visceral pleural disese. Furthermore, pleural symphysis could deteriorates normal pleural physiology and cause chronic pain. According to our previous study, stapling resection of the bulla without pleurodesis gave comparable result in recurrence comparing with articles with additional pleurodesis. The purpose of this study is to evaluate surgical outcome of thoracoscopic surgery with or without pleural abrasion and to know whether adhesive procedure is essential in the management of PSP.

Conditions

• Primary Spontaneous Pneumothorax

Interventions

Type	Name	Description
PROCEDURE	thoracoscopic surgery	stapled wedge resection of the lung mechanical pleural abrasion

Timeline

• Start date: 2006-11-01
• Primary completion: 2010-07-01
• Completion: 2011-07-01
• First posted: 2008-02-14
• Last updated: 2011-09-30

Locations

1 site across 1 country: South Korea