Clinical Trials Directory

Trials / Unknown

UnknownNCT00613561

Early Diagnosis and Stem Cell Transplantation for Severe Immunodeficiency Diseases

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
25 (estimated)
Sponsor
Ann & Robert H Lurie Children's Hospital of Chicago · Academic / Other
Sex
All
Age
11 Years
Healthy volunteers
Not accepted

Summary

The hypothesis of this study is that children with severe primary immunodeficiencies will benefit from early stem cell transplantation utilizing a reduced intensity conditioning regimen. This regimen is associated with a low risk of complications and will lead to correction of the underlying immunological defects.

Conditions

Interventions

TypeNameDescription
DRUGFludarabine, Busulfan, and Anti-Thymocyte GlobulinPatients on this study will receive 5 days of Fludarabine, 1 day of Busulfan Test Dose, 2 Days of Busulfan Regimen Dose, and 4 days of Anti-Thymocyte Globulin

Timeline

Start date
2007-12-01
Primary completion
2012-12-01
Completion
2017-12-01
First posted
2008-02-13
Last updated
2009-05-27

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00613561. Inclusion in this directory is not an endorsement.