NCT00613405

Stress and Marijuana Cue-elicited Craving and Reactivity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 87 (actual)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to explore the interaction between stress and marijuana cues, in hopes that it may lead to the development of new treatments for marijuana dependence.

Detailed description

Although use of marijuana is widespread, little research has focused on the treatment of marijuana use disorders or on predictors of relapse. Although several factors contributing to relapse have been explored in other dependencies (i.e., alcohol, cocaine), little research has focused on drug cue-related or stress-induced relapse in marijuana-dependent individuals. Cue reactivity is a construct measured in a laboratory procedure where an individual's subjective, behavioral, and physiological responses are assessed following exposure to drug-related environmental cues or stressors. Investigating the effects of drug-related environmental cues and stress in marijuana-dependent individuals will be useful in guiding treatment development.

Conditions

• Cannabis Use Disorders

Interventions

Type	Name	Description
OTHER	Stress + cue exposure	Trier Social Stress Task(TSST): subject is asked to give a talk and perform a math task in front of an audience, follwed by neutral and marijuana cue exposure.
OTHER	No stress + cue exposure	Neutral and marijuana-associated cue exposure (scripted imagery, in vivo cues).

Timeline

• Start date: 2008-01-01
• Primary completion: 2009-05-01
• Completion: 2009-05-01
• First posted: 2008-02-13
• Last updated: 2013-04-30
• Results posted: 2012-05-04

Locations

1 site across 1 country: United States