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Trials / Terminated

TerminatedNCT00611637

CMV pp65 Specific T Cell Adoptive Immunotherapy in Allogeneic Stem Cell Transplantation for Malignant Disease

A Pilot Clinical Trial of CMV pp65 Specific T Cell Adoptive Immunotherapy in Patients Who Have Undergone Allogeneic Stem Cell Transplantation for Malignant Disease

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
2 (actual)
Sponsor
H. Kim Lyerly · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the safety and feasibility of CMV specific, T cell adoptive immunotherapy in patients who have undergone allogeneic stem cell transplantation for malignant disease.

Detailed description

The primary purpose of this clinical trial is to evaluate the safety of this treatment.

Conditions

Interventions

TypeNameDescription
BIOLOGICALCMV pp65 Specific T CellsDonor derived CMV pp65 specific T cells (1 x 105 CD3+ cells/kg (maximum 1 x 107 CD3+ cells) will be infused into recipient over 10 minutes.

Timeline

Start date
2005-08-01
Primary completion
2008-02-01
Completion
2008-06-01
First posted
2008-02-11
Last updated
2012-11-12

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00611637. Inclusion in this directory is not an endorsement.

CMV pp65 Specific T Cell Adoptive Immunotherapy in Allogeneic Stem Cell Transplantation for Malignant Disease (NCT00611637) · Clinical Trials Directory