NCT00610545

Atorvastatin in Perioperative Vascular Surgery - Pilot Study

Atorvastatin 80mg Versus Atorvastatin 20mg in Perioperative Vascular Surgery to Evaluate Cardiovascular Outcomes

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of Campinas, Brazil · Academic / Other
• Sex: All
• Age: 40 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

This study is designed to determine if the use of atorvastatin (Lipitor), a member of the HMG coA reductase inhibitor class of drugs referred to as statins, will reduce cardiovascular outcomes ( mortality - myocardial infarction - stroke ) when given in high doses in comparative standard doses in the perioperative period of major vascular surgery. Abdominal aortic aneurysm , Carotid endarterectomy , Revascularization of lower limbs

Conditions

• Vascular Surgery

Interventions

Type	Name	Description
DRUG	Atorvastatin	Atorvastatin 80 mg; Use Atorvastatin for 60 days , and the vascular surgery will be made between day-7 and day-60
DRUG	Atorvastatin	Atorvastatin 20 mg; Use Atorvastatin for 60 days , and the vascular surgery will be made between day-7 and day-60

Timeline

• Start date: 2007-07-01
• Primary completion: 2008-09-01
• Completion: 2008-12-01
• First posted: 2008-02-08
• Last updated: 2009-02-16

Locations

1 site across 1 country: Brazil