NCT00607659

Immunopathogenesis of Chlamydia

Immunopathogenesis of Chlamydia Trachomatis Infection

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 29 (actual)
• Sponsor: Arkansas Children's Hospital Research Institute · Academic / Other
• Sex: Female
• Age: 11 Years – 21 Years
• Healthy volunteers: Accepted

Summary

Sexually transmitted Chlamydia trachomatis infections are a widespread public health concern due to their prevalence and potentially devastating reproductive consequences, including pelvic inflammatory disease, infertility, and ectopic pregnancy. The goal of this study is to evaluate the risk factors for adverse outcomes following genital tract infection with Chlamydia trachomatis and to evaluate whether or not the presence of C. trachomatis in the rectum act as a reservoir for infection.

Detailed description

Sexually transmitted Chlamydia trachomatis infections are a widespread public health concern due to their prevalence and potentially devastating reproductive consequences, including pelvic inflammatory disease, infertility, and ectopic pregnancy. The goal of this study is to evaluate the risk factors for adverse outcomes following genital tract infection with Chlamydia trachomatis and to evaluate whether or not the presence of C. trachomatis in the rectum act as a reservoir for infection. Our target population will be adolescent females age 11-21 evaluated at the ACH Adolescent Center who are undergoing pelvic examinations or urine screening for sexually transmitted infections (STIs). Laboratory specimens obtained will include cervical and rectal swabs, urine and blood specimens, as well as, chart review and comprehensive subject interviews in the initial data collection with follow-up evaluations at 3, 6, 12, 24 and 36 months for qualifying subjects

Conditions

• CHLAMYDIA INFECTIONS

Interventions

Type	Name	Description
OTHER	No intervention, only observational	No intervention, only observational

Timeline

• Start date: 2008-01-01
• Primary completion: 2016-01-01
• Completion: 2016-01-01
• First posted: 2008-02-06
• Last updated: 2016-04-14

Locations

1 site across 1 country: United States