Trials / Completed
CompletedNCT00606216
Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated With Chemotherapy Alone or in Combination With Radiotherapy
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 66 (actual)
- Sponsor
- Memorial Sloan Kettering Cancer Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to learn about possible changes in brain anatomy and in thinking abilities, such as memory skills, in patients with cancer who receive treatment with chemotherapy alone or in combination with total body radiation before undergoing stem cell transplantation.
Conditions
- Acute Myeloid Leukemia
- Acute Lymphoblastic Leukemia
- Acute Undifferentiated Leukemia
- Biphenotypic Leukemia
- Myelodysplastic Syndrome
- Non-Hodgkin's Lymphoma
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | MRI and cognitive evaluation | Patients will undergo a brain MRI study and a brief neuropsychological evaluation, at the time of enrollment for controls and prior to undergoing the conditioning treatment required for the stem cell transplant for patients. A follow-up MRI and cognitive evaluation will be performed approximately 12 months after the transplant for patients. |
| PROCEDURE | MRI and cognitive evaluation | Pt will undergo a Magnetic Resonance Imaging (MRI) study of the brain and a brief neuropsychological evaluation, at the time of enrollment for healthy controls and prior to undergoing the conditioning treatment required for the stem cell transplant for patients (Baseline/Time 1). |
| PROCEDURE | brain MRI study and a brief neuropsychological evaluation | A brain MRI study and a brief neuropsychological evaluation will be performed at baseline (Time 1). A follow-up MRI and cognitive evaluation will be performed and about 12 months after the baseline for healthy controls |
Timeline
- Start date
- 2007-01-01
- Primary completion
- 2015-12-01
- Completion
- 2015-12-01
- First posted
- 2008-02-01
- Last updated
- 2015-12-10
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT00606216. Inclusion in this directory is not an endorsement.