Trials / Unknown
UnknownNCT00600652
FCM Analysis GR in Steroid-Treatment Patients
Flow Cytometric Analysis of Glucocorticoid Receptor Using Monoclonal Antibody and Fluoresceinated Ligand Probes in Glucocorticoid-Resistant and -Sensitive Patients
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 150 (estimated)
- Sponsor
- Changhai Hospital · Academic / Other
- Sex
- All
- Age
- 15 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
Monitoring the GR with a GR-MoAb and FITC-Dex probes by FCM would be useful and convenient in determination GR before the steroid treatment in clinical, especially in steroid resistant states, in order to design more efficient clinical treatment protocols.
Detailed description
In order to assess the efficacy of this method, 100 patients with nephrotic syndrome and systemic lupus erythematosus receiving sufficient prednisolone thereafter and 50 age- and sex-matched normal controls will be studied.
Conditions
Timeline
- Start date
- 2006-12-01
- Primary completion
- 2010-12-01
- First posted
- 2008-01-25
- Last updated
- 2008-01-25
Source: ClinicalTrials.gov record NCT00600652. Inclusion in this directory is not an endorsement.