NCT00599950

Anterior Stromal Changes After PRK by Using Intraoperative Mitomicin C

Anterior Stromal Changes After PRK by Using Intraoperative Mitomicin C.

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Asociación para Evitar la Ceguera en México · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the confocal microscopy changes in keratocyte density at the anterior stromal after Photorefractive keratectomy (PRK) surgery, using intraoperative mitomycin C(Mitolem, LEMERY, S.A. de C.V. Mexico D.F. Reg. 136M92 SSA).

Detailed description

10 eyes of 10 patients underwent PRK,using intraoperative mitomycin C (Mitolem, LEMERY, S.A. de C.V. Mexico D.F. Reg. 136M92 SSA), and 10 eyes for the same patients underwent PRK without intraoperative mitomycin C. A central scan of the total corneal thickness was taken with the confocal microscope (Confoscan 4, Fortune Technologies, Italy) after surgery, and 1 week, 1 month, 3 months, and 6 months after surgery. Corneal epithelial thickness and the Anterior stroma morphology were analyzed by using the NAVIS software V. 3.5.0 (NIDEK, Multi-Instrument Diagnostic System, Japan).

Conditions

• Refractive Disorders

Interventions

Type	Name	Description
DRUG	Mitomycin C and Photorefractive keratectomy (PRK)	Topical mitomycin C on the corneal epithelium of patients undergoing photorefractive keratectomy (PRK)

Timeline

• Start date: 2007-01-01
• Primary completion: 2007-01-01
• Completion: 2007-11-01
• First posted: 2008-01-24
• Last updated: 2024-05-30

Locations

1 site across 1 country: Mexico