NCT00598611

Effects of 5 mg vs. 20 mg Desloratadine on Skin Lesions in Patients With Chronic Urticaria (CU)

An Exploratory Phase III, Randomised, Double-blind, Therapeutic Single Dose-related Effect, Parallel Group Study to Assess and Compare the Effects of 5 mg vs. 20 mg Desloratadine on Skin Lesions in Patients With Chronic Urticaria (CU)

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 29 (actual)
• Sponsor: Charite University, Berlin, Germany · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare urticaria lesions (size, kinetics) by thermography, volumetry and digital time lapse photography in CU patients treated with desloratadine 5 mg or desloratadine 20 mg. Hypothesis: Updosing of desloratadine (20mg) is more efficient in the treatment of urticarial lesions as compared to standard dosing (5 mg desloratadine).

Conditions

• Chronic Urticaria

Interventions

Type	Name	Description
DRUG	desloratadine	singel dose, oral, 20 mg
DRUG	desloratadine	single dose, oral, 5 mg

Timeline

• Start date: 2007-09-01
• Primary completion: 2009-08-01
• Completion: 2009-08-01
• First posted: 2008-01-22
• Last updated: 2012-05-31

Locations

1 site across 1 country: Germany