NCT00596999

A Single-arm Safety Study of Transplantation Using Umbilical Cord Blood and Human Placental-derived Stem Cells From Partially Matched Related Donors in Persons With Certain Malignant Blood Diseases and Non-malignant Disorders

A Single-Arm Study to Assess the Safety of Transplantation With Umbilical Cord Blood Augmented With Human Placental-Derived Stem Cells From Partially Matched Related Donors in Subjects With Certain Malignant Hematologic Diseases and Non-Malignant Disorders

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 6 (estimated)
• Sponsor: Celgene Corporation · Industry
• Sex: All
• Age: 55 Years
• Healthy volunteers: Not accepted

Summary

To investigate the safety of partially matched related human placental-derived stem cells (HPDSC) administered in conjunction with umbilical cord blood (UCB) stem cells from the same donor in subjects with various malignant or nonmalignant disorders potentially curable with stem cell transplantation and to assess potential restoration of normal hematopoiesis and immune function in subjects with these disorders

Conditions

• Hematologic Malignancies

Interventions

Type	Name	Description
PROCEDURE	UCB and HPDSC	single dose of UCB followed by one unit of HPDSC

Timeline

• Start date: 2007-05-01
• Primary completion: 2013-07-01
• Completion: 2013-12-01
• First posted: 2008-01-17
• Last updated: 2012-04-10

Locations

1 site across 1 country: United States