NCT00596362

Treatment With Intravitreal Avastin for Large Uveal Melanomas

Neoadjuvant Treatment With Intravitreal Avastin for Large Uveal Melanomas

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1 (actual)
• Sponsor: Memorial Sloan Kettering Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to test the safety and effectiveness of Avastin introduced into the inside of the eyeball in causing shrinkage of the uveal melanoma (tumor of the eye). Avastin is an anti-cancer drug specially designed to shrink blood vessels within tumors.

Conditions

• Uveal Melanoma

Interventions

Type	Name	Description
DRUG	AVASTIN	a single injection of Avastin at the outpatient clinic. This will be done as follows: the pupil in the eye being treated will be enlarged with a liquid solution. Thirty minutes later, a numbing solution and then a cleansing solution will be put in to the eye. Finally, an injection of Avastin will be given into the eye. Right after this injection, your eye will be examined by your doctor. The pressure in your eye will also be tested before and after the injection. Patients will use antibiotic drops for 5 days following the injection. Following the injection, you will have weekly examinations for four weeks in the office.

Timeline

• Start date: 2007-04-01
• Primary completion: 2008-06-01
• Completion: 2008-06-01
• First posted: 2008-01-17
• Last updated: 2016-06-17
• Results posted: 2015-04-14

Locations

1 site across 1 country: United States