NCT00594620

Soy Derivatives for Control of Hot Flashes in Men on Androgen Deprivation Therapy

A Prospective Trial of Soy Derivatives for Control of Hot Flashes in Men on Androgen Deprivation Therapy

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: University of Kansas Medical Center · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To determine the efficacy of soy/isoflavone supplementation on hot flashes in men who are being treated with luteinizing hormone-releasing hormone (LHRH) agonist therapy for control of advanced prostate cancer

Detailed description

Literature has shown that low dose estrogens can control hot flashes in men on androgen deprivation but with a high risk of thromboembolic events. Soy derivatives that contain isoflavones, a type of phytoestrogen, have been evaluated in peri-menopausal women as a possible safer alternative to synthetic estrogens but there has not been a similar study performed on their effect in men on androgen deprivation therapy for prostate cancer.

Conditions

• Prostate Cancer

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Flav-ein capsules	Soy/isoflavone supplementation
DRUG	Placebo	Placebo

Timeline

• Start date: 2004-08-01
• Primary completion: 2010-04-01
• Completion: 2010-04-01
• First posted: 2008-01-15
• Last updated: 2022-02-14
• Results posted: 2022-02-08

Locations

1 site across 1 country: United States