Clinical Trials Directory

Trials / Completed

CompletedNCT00592982

Bisphosphonate-Associated Jaw Osteonecrosis and PET Imaging

Status
Completed
Phase
Study type
Observational
Enrollment
25 (actual)
Sponsor
University of Arkansas · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

1. Bisphosphonate-associated osteonecrosis of the jaw(ONJ)is detectable by positron emission tomography(PET). 2. Bisphosphonate-associated ONJ can be diagnosed and characteristically differentiated from other bony pathologies of the jaw(osteomyelitis, osteolytic lesions, and osteoradionecrosis)by PET imaging.

Detailed description

Is to review medical records of approximately 1000 patients with bisphosphonate-associated ONJ who have had PET imaging at the time of diagnosis. Also to review medical records of patients who have been diagnosed with jaw osteomyelitis, osteoradionecrosis, and cancerous lytic lesions who received PET imaging at the time of diagnosis. If sufficient information regarding presentation and treatment cannot be obtained form the medical record, approximately 300 patients will contacted by mail (and phone if necessary) by the PI or sub-investigators to question them regarding the onset of symptoms, treatment interventions, and outcomes.

Conditions

Timeline

Start date
2006-10-01
Primary completion
2013-08-01
Completion
2013-08-01
First posted
2008-01-14
Last updated
2013-10-25

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00592982. Inclusion in this directory is not an endorsement.