NCT00592228

Proper Fractional Flow Reserve Criteria for Intermediate Lesions in the Era of Drug-eluting Stent

Deferral of Angioplasty According to Fractional Flow Reserve vs. Routine Drug-eluting Stent Implantation in Intermediate Coronary Stenosis

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 250 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Angiographic evaluation for intermediate lesions is not always accurate. Fractional flow reserve-guided deferral strategy for these lesions showed the same event rate as routine intervention strategy. However, proper FFR criterion for these lesions in the era of drug-eluting stent is not known. This study sought to evaluate the clinical outcomes of intermediate lesions according to FFR and compare those of FFR-guided intervention with routine drug-eluting stent implantation strategy.

Conditions

• Coronary Angiography
• Drug-eluting Stents
• Fractional Flow Reserve, Myocardial

Interventions

Type	Name	Description
DEVICE	Cypher, Taxus or Endeavor	percutaneous drug-eluting stent implantation, 1. FFR group: if FFR\<0.75 2. Routine DES group

Timeline

• Start date: 2007-01-01
• Primary completion: 2009-01-01
• Completion: 2009-01-01
• First posted: 2008-01-11
• Last updated: 2010-12-21

Locations

1 site across 1 country: South Korea