NCT00590317

Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency Department

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 64 (actual)
• Sponsor: Emory University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study will compare the effect of prochlorperazine and ondansetron for the treatment of nausea and vomiting in the emergency department.

Detailed description

Nausea and vomiting can be common symptoms in the emergency department (ED). Antiemetics, agents to treat nausea and vomiting, include phenothiazine derivatives, prokinetic agents, and 5-HT3 antagonists. There have been limited studies on the use of these agents in the ED, and no direct comparisons to 5-HT3 antagonists have been published to date. Inclusion Criteria: Patients presenting to the ED with at least one of the following * nausea * vomiting documented in the ED

Conditions

• Nausea and Vomiting

Interventions

Type	Name	Description
DRUG	Prochlorperazine	Patients receiving Prochlorperazine
DRUG	Ondansetron	Patients receiving Ondansetron

Timeline

• Start date: 2005-03-01
• Primary completion: 2008-09-01
• Completion: 2008-09-01
• First posted: 2008-01-10
• Last updated: 2014-05-19
• Results posted: 2014-05-19

Locations

2 sites across 1 country: United States