NCT00587028

Cathartic-Free DECT Colonography for Detection of Colonic Polyps

Cathartic-Free Dual Energy Computerized Tomography (DECT) Colonography.

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 12 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 40 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

Asses the clinical performance of dual-energy CTC for the detection of larger polyps 1 cm or larger without cathartic preparation.

Detailed description

Determine the feasibility to differentiate polyps from stool with or without the use of contrast agents and to assess the feasibility and accuracy of dual energy techniques in a pilot patient study. 1.1 Formulate algorithms that use dual-energy information to quantitatively measure specific material density of colon polyps in physics based simulation. 1.2 Determine optimal scanning parameters on prototype CT equipment. 2.1 Measure the material composition density and Hounsfield number of polyps with and without simulated contrast enhancement. 2.2 Measure the accuracy of dual-energy techniques to differentiate between polyps and stool and if needed using a combination of simulated intravenous enhanced polyps and contrast material tagged stool. 3.0 Asses the clinical performance of dual-energy CTC for the detection of larger polyps 1 cm or larger without cathartic preparation.

Conditions

• Colonic Polyps

Timeline

• Start date: 2007-02-01
• Primary completion: 2008-12-01
• Completion: 2008-12-01
• First posted: 2008-01-07
• Last updated: 2016-01-22

Locations

2 sites across 1 country: United States