NCT00586885

Effects of Alanine in Patients With Nonalcoholic Steatohepatitis

A Pilot Study: Therapeutic Effect of L-Alanine in Patients With Nonalcoholic Steatohepatitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: Keith D Lindor, M.D. · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Purpose of this study is to assess the therapeutic efficacy of L-alanine in improving biological and histological findings by administrating 6-18g/day L-alanine for one year. We will also assess the safety and toxicity profile of long-term administration of L-alanine.

Conditions

• Nonalcoholic Steatohepatitis

Interventions

Type	Name	Description
DRUG	L-alanine	6g of L-alanine (powder)once per day for the first month, twice per day for the second month, then three times per day from the third month for 10 months.

Timeline

• Start date: 2004-02-01
• Primary completion: 2006-06-01
• Completion: 2006-06-01
• First posted: 2008-01-07
• Last updated: 2012-10-11

Locations

1 site across 1 country: United States