NCT00584649

Ablation of Inappropriate Sinus Tachycardia

Ablation of Inappropriate Sinus Tachycardia Syndrome by Targeting Cardiac Neural Input

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: University of Oklahoma · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Hypothesis- Radiofrequency ablation, targeting the sympathetic input of the sinus node identified by 20Hz stimulation at the junction of the superior vena cava and the right atrium, will effectively reduce sinus rate acutely and will reduce palpitations due to inappropriate sinus tachycardia without the need for pacemaker implantation due to sinus node dysfunction post ablation.

Detailed description

Inappropriate sinus tachycardia syndrome describes a condition in which a patient's heart rate is intermittently (or persistently) higher than expected for the physiological circumstances, with ECG appearance indistinguishable from normal sinus rhythm, after the exclusion of medical conditions causing sinus tachycardia. Hypothesis- Radiofrequency ablation, targeting the sympathetic input of the sinus node identified by 20Hz stimulation at the junction of the superior vena cava and the right atrium, will effectively reduce sinus rate acutely and will reduce palpitations due to inappropriate sinus tachycardia without the need for pacemaker implantation due to sinus node dysfunction post ablation.

Conditions

• Inappropriate Sinus Tachycardia

Interventions

Type	Name	Description
PROCEDURE	electrophysiology study and radiofrequency ablation	stimulation protocol searching for the neural inputs to the sinus node region and radiofrequency ablation of neural input to the heart

Timeline

• Start date: 2004-04-01
• Primary completion: 2020-07-07
• Completion: 2020-07-07
• First posted: 2008-01-02
• Last updated: 2024-04-01

Locations

1 site across 1 country: United States