NCT00584428

High Dose Chemo With Autologous BMT for Treatment of Metastatic Breast Cancer

High Dose Chemotherapy With Autologous Bone Marrow Transplantation in the Treatment of Metastatic Breast Cancer

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 61 (actual)
• Sponsor: University of Oklahoma · Academic / Other
• Sex: Female
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the response rate and the response duration of high dose chemotherapy with autologous bone marrow transplantation as intensification following induction chemotherapy in metastatic breast cancer and to evaluate prospectively the subdivision of patients with metastatic breast cancer according to prognostic groups.

Detailed description

There are 2 phases to this study: 1) Induction- which consists of the administration of chemotherapeutic drugs- at the end of this phase if the cancer has responded, bone marrow will be collected and frozen untol ready for re-infusion; 2) 2nd phase- involves high-doses of chemotherapy followed by infusion of bone marrow cells

Conditions

• Breast Neoplasms

Interventions

Type	Name	Description
PROCEDURE	High-Dose Chemo with Autologous BMT	Carboplatin/VP-16/Cytoxan for women 18-59 and Carboplatin/Thiotepa/Cytoxan for women 60-70

Timeline

• Start date: 1992-06-01
• Primary completion: 2002-03-01
• Completion: 2002-03-01
• First posted: 2008-01-02
• Last updated: 2019-11-25

Locations

1 site across 1 country: United States