NCT00582036

Glucose Control In Hematopoetic Stem Cell Transplant

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: University of Oklahoma · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To determine whether intensive glucose control results in improved mortality and reduced hospital stay length by performing a randomized trial of intensive glucose management (blood glucose goal 110 mg/dl) using continuous IV insulin and glucose vs. non-intensive glucose management (goal 200 mg/dl)

Detailed description

TO determine whether there are fewer infections, days without a fever, days on antibiotics given for an infection and time to marrow engraftment are improved by intensive glucose management; and to determine whether there is evidence of a reduction in measures of inflammation in patients randomized to intensive glucose management and whether reduction of inflammation is associated with outcome.

Conditions

• Hyperglycemia
• Hematopoietic Stem Cell Transplantation

Interventions

Type	Name	Description
DRUG	Regular Insulin	Use of sliding scale insulin as per Appendix 1
DEVICE	Deployment of the MiniMed Paradigm monitoring device	Automated insulin delivery system

Timeline

• Start date: 2007-02-01
• Primary completion: 2009-05-01
• Completion: 2009-05-01
• First posted: 2007-12-28
• Last updated: 2024-07-03
• Results posted: 2011-04-22

Locations

1 site across 1 country: United States