NCT00575380

Study of AzaSite Versus Vigamox Concentrations in the Conjunctiva and Aqueous Humor in Subjects Undergoing Routine Cataract Surgery

A Multi-Center, Open-Label, Randomized Study of the Pharmacokinetics of Azithromycin Versus Moxifloxacin in Conjunctiva and Aqueous Humor Following Single or Multiple Ocular Administration of AzaSite Ophthalmic Solution, 1% or Vigamox in Subjects Undergoing Routine Cataract Surgery

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 116 (actual)
• Sponsor: Merck Sharp & Dohme LLC · Industry
• Sex: All
• Age: 21 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the drug concentrations in the conjunctiva and aqueous humor of AzaSite™ compared to Vigamox® in subjects undergoing routine cataract surgery

Conditions

• Bacterial Infections
• Eye Infections
• Cataract Extraction

Interventions

Type	Name	Description
DRUG	AzaSite Eye Drops	One drop two times a day for two days and once a day for the next five days.
DRUG	Vigamox Eye Drops	One drop three times a day for seven days

Timeline

• Start date: 2007-12-01
• Primary completion: 2008-06-01
• First posted: 2007-12-18
• Last updated: 2011-09-22
• Results posted: 2009-09-16

Locations

13 sites across 1 country: United States