NCT00575354

Comparison of Sevoflurane and Isoflurane Anesthesia for Benign Breast Tumor Excision

Anesthesia With Sevoflurane and Isoflurane for Excision Surgeries in Benign Breast Tumors

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 500 (actual)
• Sponsor: Nanjing Medical University · Academic / Other
• Sex: Female
• Age: 18 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

Generally, benign breast tumors are excised under the local anesthesia. But such action was so invasive that every patient would experience the physiological and psychological stimuli unavoidably. Sevoflurane was advised as a better inhalational anesthesic for its "easy come,easy go" property during short-lasting operations than isoflurane. We purposed that sevoflurane would be a superior anesthesic for benign breast tumor excision than isoflurane with relative less alteration in hemodynamics, less postoperative side effects and easily-control the depth of anesthesia.

Conditions

• Breast Neoplasms

Interventions

Type	Name	Description
DRUG	Sevoflurane	3-6% sevoflurane inhaled for anesthesia induction, and 2-3% sevoflurane was used to maintain the anesthesia till the end of the operation.
DRUG	Isoflurane	3-6% isoflurane inhaled for anesthesia induction, and 2-3% isoflurane was used to maintain the anesthesia till the end of the operation.

Timeline

• Start date: 2007-03-01
• Primary completion: 2007-12-01
• Completion: 2007-12-01
• First posted: 2007-12-18
• Last updated: 2008-04-21

Locations

1 site across 1 country: China