NCT00571831

The Effect of a Blue Light Filtering IOL

The Effect of a Blue Light Filtering Intraocular Lens on Blood Retinal Barrier After Cataract Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Showa University · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

To compare the effect on blood retinal barrier disruption 3 and 12 months after implantation of either a blue light filtering intraocular lens(blue-filtering IOL) or an ultraviolet light filtering intraocular lens(UV-filtering IOL).

Detailed description

The following parameters were measured for evaluation of blood retinal barrier disruption. * the incidence of macular leakage by fluorescence angiography (FA) * the mean fluorescein concentration in the vitreous by fluorophotometry (VFP) * the thickness of the macula by optical coherence tomography (OCT) Results * the incidence fo macular leakage decreased significantly from 24%(3 months) to 5% (12 months) in the blue-filtering IOL group (P\<0.05), and was significantly lower compared with the UV-filtering IOL group at 12 months. * the VFP significantly decreased in both group from 3 to 12 months. * the OCT decreased from 175 (3 months) to 166 um (12 months) in the blue- filtering IOL group.

Conditions

• to Compare the Effect of Two Types of IOLs
• on the Incidence of Cystoid Macular Edema
• After Cataract Surgery

Interventions

Type	Name	Description
PROCEDURE	intraocular lens implantation	Intraocular lens implantation

Timeline

• Start date: 2003-02-01
• Completion: 2005-03-01
• First posted: 2007-12-12
• Last updated: 2007-12-12

Locations

1 site across 1 country: Japan