NCT00571389

A Biospecimen Collection Study of Leukapheresis-Derived Circulating Tumor Cells, Immune Cells, and Progenitor Cells.

A Biospecimen Collection Study to Facilitate Development of an Ex-Vivo Device Platform for Culture, Immune Assay, and Biobanking of Leukapheresis-Derived Circulating Tumor Cells, Immune Cells, and Progenitor Cells.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,500 (estimated)
• Sponsor: BioCytics, Inc. · Industry
• Sex: All
• Age: 5 Years
• Healthy volunteers: Accepted

Summary

Primary Objective: This is a study to investigate the feasibility of harvesting, expanding, and selecting T lymphocytes from cancer patients and healthy volunteers. The preliminary objective of this study is aimed at selecting PD-1+ and CTLA4+ T cells and other cellular fractions from peripheral blood of cancer patients and healthy volunteers by using specific conjugated antibodies, evaluating their functional ex vivo anti-tumor cytotoxicity against targeted autologous tumor cells.

Conditions

• Solid Tumor, Adult
• Healthy Donors
• COVID-19 Donors

Timeline

• Start date: 2007-11-01
• Primary completion: 2030-02-01
• Completion: 2030-02-01
• First posted: 2007-12-12
• Last updated: 2026-03-18

Locations

1 site across 1 country: United States