Trials / Completed
CompletedNCT00569049
Molecular Analysis of Breast Cancer
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 788 (actual)
- Sponsor
- Stanford University · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
This is a research-based study that is looking at the biologic features of breast tissue, lymph node tissue, or blood in order to study breast cancer development growth, and spread. Through tissue and/or blood samples we hope to gain further knowledge and understanding of how to improve diagnosis and treatment of breast cancer by identifying the molecular markers that predict clinical outcome and response to therapy.
Detailed description
The tissue obtained in this protocol will be used for genome-wide examination of DNA, RNA expression profiling, proteomic analyses, isolation and analyses of normal and cancer stem cells, isolation and analyses of circulating tumor cells, possible analyses of immune cells, and possible analyses of serum factors. The tissue may also be used to develop patient-specific cell culture models or mouse xenograft models of breast cancer for biologic study of tumor progression and metastases and for therapeutic testing. In general, the tissue will be used in studies that will molecularly classify tumors, identify prognostic markers, identify potential therapeutic markers, identify potential treatment targets, and help us better understand the biology and specific role played by different tumor cells in the metastatic process. The ultimate goal is to use molecular analyses to improve the diagnosis and treatment of breast cancer.
Conditions
- Breast Cancer
- Breast Cancer Non-invasive Breast Cancer
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | breast tissue, lymph node tissue or blood | Molecular Analyses of samples |
Timeline
- Start date
- 1996-05-01
- Primary completion
- 2011-07-01
- Completion
- 2011-07-01
- First posted
- 2007-12-06
- Last updated
- 2025-02-11
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00569049. Inclusion in this directory is not an endorsement.