NCT00568217

Antipyretics for Preventing Recurrences of Febrile Seizures

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 231 (actual)
• Sponsor: University of Oulu · Academic / Other
• Sex: All
• Age: 3 Months – 4 Years
• Healthy volunteers: Not accepted

Summary

We wanted to find out if the early use of antipyretics is capable in preventing recurrences of febrile seizures. When a child has had his/her first febrile seizure, the parents were instructed to give him/her antipyretic medication every time when the child had a new episode of fever during two years.

Conditions

• Recurrence of Febrile Seizure

Interventions

Type	Name	Description
DRUG	Diclofenac, Paracetamol, Ibuprofen	Immediately if temperature \> 38 degree Celsius, diclofenac suppository 1,5 mg/kg once or placebo suppository After eight hours, if temperature still \< 38 degree Celsius, acetaminophen mixture 15 mg/kg up to four times a day, or ibuprofen mixture 10 mg/kg up to four times a day, or placebo mixture up to four times a day as long as temperature \< 38 degree Celsius

Timeline

• Start date: 1997-09-01
• Completion: 2005-08-01
• First posted: 2007-12-05
• Last updated: 2007-12-11

Locations

1 site across 1 country: Finland