Clinical Trials Directory

Trials / Completed

CompletedNCT00568022

A Phase I Study of Ixabepilone in Combination With Capecitabine in Japanese Patients With Metastatic Breast Cancer

A Phase I Study of Ixabepilone in Combination With Capecitabine in Japanese Patients With Metastatic Breast Cancer Previously Treated With an Anthracycline and a Taxane

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
9 (actual)
Sponsor
R-Pharm · Industry
Sex
Female
Age
20 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the dose-limiting toxicity (DLT), maximum tolerated dose (MTD) and recommended Phase II dose of ixabepilone in combination with capecitabine in Japanese participants with metastatic breast cancer.

Conditions

Interventions

TypeNameDescription
DRUGIxabepiloneIxabepilone: Intravenous (IV) Solution, IV, 32(40)mg/m\^2, once every 3 weeks, up to 6 cycles
DRUGCapecitabineCapecitabine: Tablets, Oral, 1650(2000)mg/m\^2, twice daily for 2 weeks, one week off, up to 6 cycles

Timeline

Start date
2008-02-01
Primary completion
2010-01-01
Completion
2010-01-01
First posted
2007-12-05
Last updated
2016-03-10
Results posted
2011-08-17

Locations

4 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT00568022. Inclusion in this directory is not an endorsement.