Trials / Completed
CompletedNCT00567593
Gene Regulation by Thiazolidinediones
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- James Lewis · Academic / Other
- Sex
- All
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to determine the effect of rosiglitazone on the genes of the colon
Detailed description
The primary aim of the study is to examine the effect of rosiglitazone (Avandia) on gene regulation in colonic epithelium in the absence of pathologic acute and chronic intestinal inflammation. The secondary aims are to determine the effect of rosiglitazone (Avandia) therapy on T cell activation and cytokine expression in the absence of pathologic acute and chronic intestinal inflammation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Rosiglitazone | 8mg tablet once a day for 14 days |
Timeline
- Start date
- 2007-10-01
- Primary completion
- 2008-03-01
- Completion
- 2008-03-01
- First posted
- 2007-12-05
- Last updated
- 2016-08-01
- Results posted
- 2014-05-08
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00567593. Inclusion in this directory is not an endorsement.