Trials / Completed
CompletedNCT00565240
Mid-luteal Phase Synchronization of Ovarian Folliculogenesis in Women
Mid-luteal Phase Synchronization of Ovarian Folliculogenesis in Women Protocol: WHIRL-07-2971
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 41 (actual)
- Sponsor
- University of Saskatchewan · Academic / Other
- Sex
- Female
- Age
- 18 Years – 35 Years
- Healthy volunteers
- Accepted
Summary
We hypothesize that administration of an aromatase inhibitor (AI) and hormonal contraceptives (HC) in the mid-luteal phase of the menstrual cycle will result in atresia of the follicles in the extant wave and cause synchronous re-emergence of a new follicular wave. We anticipate that this will provide us with information to facilitate the development of a new method for ovarian synchronization; a safer, more effective ovulation induction therapy; a new method for emergency contraception; and a greater understanding of human folliculogenesis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Marvelon | oral contraceptive |
| DRUG | Nuvaring | contraceptive vaginal ring |
| DRUG | Letrozole | Aromatase Inhibitors |
Timeline
- Start date
- 2007-11-01
- Primary completion
- 2009-09-01
- Completion
- 2009-09-01
- First posted
- 2007-11-29
- Last updated
- 2010-04-22
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT00565240. Inclusion in this directory is not an endorsement.