NCT00560898

Comparison of Two Multi-Purpose Solution and Lens Material Combinations on Corneal Barrier Function

Comparison of Two Multi-Purpose Solution and Contact Lens Material Combinations on Human Corneal Barrier Function

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: Southern California College of Optometry at Marshall B. Ketchum University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to measure the relative "barrier" function of the top layer of the cornea (called the epithelium), or the degree to which the cornea can prevent the penetration of the colored dye sodium fluorescein into the eye. This is a clinical investigation of the effect on corneal barrier function following wear of two contact lens materials and two contact lens care systems, approved for marketing in the US by the Food and Drug Administration. These contact lenses will be worn for two hours, following soak in one of two marketed contact lens disinfecting solutions. Approximately 25 young, adapted contact lens wearers will participate.

Conditions

• Contact Lens Disinfecting Solutions

Interventions

Type	Name	Description
DRUG	ProClear Lens Material soaked in ReNu Multiplus Multipurpose Solution	Contact lens soaked in multipuprpose solution for 8 hours, then worn for two hours
DRUG	Acuvue Advance Lens Material soaked in ReNu Multiplus Multipurpose Solution	Contact lens soaked in multipuprpose solution for 8 hours, then worn for two hours
DRUG	Acuvue Advance Lens Material soaked in Optifree RepleniSH Multipurpose Solution	Contact lens soaked in multipuprpose solution for 8 hours, then worn for two hours
DRUG	ProClear Lens Material soaked in Optifree RepleniSH Multipurpose Solution	Contact lens soaked in multipuprpose solution for 8 hours, then worn for two hours

Timeline

• Start date: 2007-09-01
• Primary completion: 2007-12-01
• Completion: 2008-03-01
• First posted: 2007-11-20
• Last updated: 2008-05-20

Locations

1 site across 1 country: United States