NCT00560534

Whole Body Magnetic Resonance Angiography With Subsystolic Venous Compression

Whole Body Magnetic Resonance Angiography in Patients With Symptomatic Peripheral Ischemia. Experience With Venous Compression.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 36 (estimated)
• Sponsor: Copenhagen University Hospital at Herlev · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To investigate the diagnostic performance of whole body magnetic resonance angiography (WB-MRA) using subsystolic venous compression of the thigh.

Detailed description

WB-MRA is an examination that can evaluate the arteries from head to feet. Timing of the injected bolus of contrast medium can be difficult, especially in the legs. As the result of the WB-MRA depends on the contrast medium only being in the arteries at the time of examination, the use of venous compression is a possible way of overcoming the problem of early venous filling, that can hamper the diagnostic value of the examination. Venous compression is performed with a blod pressure cuff around the thighs. It is inflated to subsystolic pressure (45 mm Hg). This elevated pressure leads to filling of the lower leg arteries and late venous filling.

Conditions

• Atherosclerosis
• Intermittent Claudication

Interventions

Type	Name	Description
PROCEDURE	Whole body magnetic resonance angiography	Magnetic resonance angiography using a paramagnetic contrast agent.Venous compression performed with a blood-pressure cuff around both thighs.

Timeline

• Start date: 2008-06-01
• Completion: 2009-03-01
• First posted: 2007-11-19
• Last updated: 2009-08-19

Locations

1 site across 1 country: Denmark