Clinical Trials Directory

Trials / Completed

CompletedNCT00559455

Phase II Study of Eloxatin+5-FU/LV in Patients With Unresectable Hepatocellular Carcinoma

Phase II Study of Oxaliplatin + 5-FluoroUracil/Leucovorin (Eloxatin+5-FU/LV) in Patients With Unresectable Hepatocellular Carcinoma

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
38 (actual)
Sponsor
Sanofi · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

Primary objective: To determine the Tumor Response Rate of patients with hepatocellular carcinoma treated with the combination chemotherapy of Eloxatin+5-FU/LV Secondary objective: To evaluate time to progression, 6month survival, overall survival, safety and tolerability of patients with hepatocellular carcinoma treated with the combination chemotherapy of Eloxatin+5-FU/LV

Conditions

Interventions

TypeNameDescription
DRUGOxaliplatin85mg/m², 2 hours IV infusion, Day 1; Every 2 weeks
DRUGFluorouracil400mg/m², 2 hours IV bolus, Day 1; 22 hours continuous IV infusion 600mg/m², Day 1 and Day 2; Every 2 weeks
DRUGLeucovorin200mg/m², Day 1 and Day 2; Every 2 weeks

Timeline

Start date
2007-09-01
Primary completion
2010-01-01
Completion
2010-01-01
First posted
2007-11-16
Last updated
2011-06-28

Locations

1 site across 1 country: South Korea

Source: ClinicalTrials.gov record NCT00559455. Inclusion in this directory is not an endorsement.