Clinical Trials Directory

Trials / Completed

CompletedNCT00558649

A Pilot Study to Evaluate the Safety and Immunogenicity of Low Dose Flu Vaccines

A Pilot, Controlled, Comparative and Single Blinded Study to Evaluate the Safety and Immunogenicity of Low Dose Flu Vaccines Administered Intradermally Using Microneedle Injectors as Compared With Standard Dose Intramuscular Flu Vaccines as Reference.

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
180 (actual)
Sponsor
NanoPass Technologies Ltd · Industry
Sex
All
Age
18 Years – 40 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to determine whether low dose flu vaccines delivered with microneedles into the skin (intradermally) are effective.

Detailed description

Influenza vaccination is the primary method for preventing influenza and its severe complications. Previous clinical studies demonstrated that delivery of vaccines intradermally (into the skin) can achieve good efficacy even with lower doses of the vaccine. Comparison: Low dose flu vaccine delivered intradermally with a microneedle device compared to the standard dose flu vaccine delivered intramuscularly (into the muscle) with a regular needle.

Conditions

Interventions

TypeNameDescription
BIOLOGICALFlu Vaccine (FLUARIX®)Influenza Virus Vaccine, FLUARIX®, 2006-2007 Formula

Timeline

Start date
2007-05-01
Primary completion
2007-09-01
Completion
2007-12-01
First posted
2007-11-15
Last updated
2013-05-10

Source: ClinicalTrials.gov record NCT00558649. Inclusion in this directory is not an endorsement.