NCT00557752

Efficacy of Non-Invasive Mechanical Ventilation in Early Hypoxia Secondary to Thoracic Trauma

Non-Invasive Ventilation in Early Severe Posttraumatic Hypoxia: a Randomized Controlled Trial

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Hospital Virgen de la Salud · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

* Severe post-traumatic hypoxia is mainly due to lung contusion. The intubation rate of these patients is near 20%. * Treatment before intubation is needed, is based on pain control with epidural anesthesia and oxygen. * The investigators' hypothesis is that adding non-invasive mechanical ventilation to the standard treatment can reduce the intubation rate if applied early in the course of the disease. * As thoracic trauma is often associated with injuries in other body regions that may increase the complications of the technique, specific contraindications have been described.

Conditions

• Post-Traumatic Respiratory Failure

Interventions

Type	Name	Description
DEVICE	Non-invasive ventilation	Applied continuously for the first 24 hours, then every 24 hours, trial of discontinuation. Interface specific for the associated injuries.

Timeline

• Start date: 2005-09-01
• Primary completion: 2008-06-01
• Completion: 2008-06-01
• First posted: 2007-11-14
• Last updated: 2009-02-09

Locations

2 sites across 1 country: Spain