Clinical Trials Directory

Trials / Completed

CompletedNCT00553696

Study Of Sunitinib With S-1 And Cisplatin For Gastric Cancer

A Phase 1 Study Of Sunitinib In Combination With S-1 And Cisplatin In Patients With Advanced Or Metastatic Gastric Cancer

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
27 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
20 Years
Healthy volunteers
Not accepted

Summary

To assess the maximal tolerated dose (MTD) and overall safety of sunitinib when administered in combination with S-1 and Cisplatin in patients with advanced/metastatic gastric cancer.

Conditions

Interventions

TypeNameDescription
DRUGCisplatinCisplatin 60 mg/m2 on day 1 of each 28 day cycle
DRUGS-1S-1 80 mg/m2 on days 1-21 of each 28 day cycle
DRUGSunitinibSunitinib 25 mg, 37.5 mg and 50 mg daily S-1 80 mg/m2 on days 1-21 of each 28 day cycle Cisplatin 60 mg/m2 on day 1 of each 28 day cycle

Timeline

Start date
2007-11-01
Primary completion
2009-07-01
Completion
2014-03-01
First posted
2007-11-05
Last updated
2015-03-13
Results posted
2015-03-13

Locations

3 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT00553696. Inclusion in this directory is not an endorsement.