Clinical Trials Directory

Trials / Completed

CompletedNCT00551876

Study Evaluating the Efficacy and Safety of Simvastatin Alone Compared With Simvastatin Plus Ezetimibe in Type 2 Diabetic Patients (0653-021)(COMPLETED)

A Randomized, Double-Blind, Parallel, Multicenter Study to Evaluate the Efficacy and Safety of Simvastatin Monotherapy Compared With Simvastatin Plus Ezetimibe (SCH 58235) in Type 2 Diabetic Patients Treated With Thiazolidinediones

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
214 (actual)
Sponsor
Organon and Co · Industry
Sex
All
Age
30 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine if the addition of ezetimibe 10 mg daily to ongoing 20 mg simvastatin daily will reduce LDL Cholesterol to a greater extent than increasing the dose of simvastatin to 40 mg daily in Type 2 diabetics treated with Thiazolidinediones (TZD).

Conditions

Interventions

TypeNameDescription
DRUGMK0653, ezetimibe / Duration of Treatment: 30 Weeks
DRUGComparator : ezetimibe (+) simvastatin / Duration of Treatment: 30 Weeks

Timeline

Start date
2001-12-01
Primary completion
2003-01-01
Completion
2003-01-01
First posted
2007-10-31
Last updated
2024-08-15

Source: ClinicalTrials.gov record NCT00551876. Inclusion in this directory is not an endorsement.